Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.361


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
Dmap1 66233 DNA methyltransferase 1-associated protein 1
Ncor1 20185 nuclear receptor co-repressor 1
Ncor2 20602 nuclear receptor co-repressor 2
Smarca1 93761 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,
Smarca5 93762 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,
Smarcc2 68094 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smarca1chrX_-_45245608-0.531.3e-14Click!
Ncor2chr5_-_125659422-0.312.4e-05Click!
Smarca5chr8_-_832628810.231.9e-03Click!
Dmap1chr4_-_1173548290.223.2e-03Click!
Ncor1chr11_-_62206116-0.181.6e-02Click!
Smarcc2chr10_+_127896244-0.163.4e-02Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_9046362 53.819 NM_007807
Cybb
cytochrome b-245, beta polypeptide
chr7_-_128217980 52.800 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chr11_+_33946927 51.928 Lcp2
lymphocyte cytosolic protein 2
chr4_-_133650937 51.069 NM_013706
Cd52
CD52 antigen
chr6_-_129422702 48.081 NM_020008
Clec7a
C-type lectin domain family 7, member a
chr6_-_16848352 46.555 NM_031198
Tcfec
transcription factor EC
chr3_+_95330700 43.055 NM_021281
Ctss
cathepsin S
chr6_-_16848314 42.411 Tcfec
transcription factor EC
chr9_+_5298516 41.341 NM_009807
Casp1
caspase 1
chr8_+_90818102 40.981 NM_001037724
Adcy7
adenylate cyclase 7
chr5_-_134705423 34.796 NM_010876
Ncf1
neutrophil cytosolic factor 1
chr4_-_155574875 34.597 NM_015783
Isg15
ISG15 ubiquitin-like modifier
chr11_+_33947115 33.209 NM_010696
Lcp2
lymphocyte cytosolic protein 2
chr1_-_146096156 30.919 NM_015811
Rgs1
regulator of G-protein signaling 1
chr11_-_83343962 30.912 NM_013653
Ccl5
chemokine (C-C motif) ligand 5
chrX_+_83115611 30.654 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr7_+_86058817 30.334 Isg20
interferon-stimulated protein
chr4_+_144482722 29.897 NM_001172424
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr12_-_32893074 29.231 NM_001146201
NM_020272
NM_001146200
Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr16_+_35939047 29.093 Parp9
poly (ADP-ribose) polymerase family, member 9
chr8_+_74676812 28.498


chr7_+_29225955 27.959 NM_001039192
Gmfg
glia maturation factor, gamma
chrX_+_104344265 27.656 NM_001122596
A630033H20Rik
RIKEN cDNA A630033H20 gene
chrX_+_104284572 27.497 NM_172435
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chr2_+_43604343 27.455 NM_153820
NM_001025377
Arhgap15

Rho GTPase activating protein 15

chr8_+_123263681 26.963 Irf8
interferon regulatory factor 8
chr14_+_45607785 26.868 NM_008964
Ptger2
prostaglandin E receptor 2 (subtype EP2)
chr11_-_48684659 26.618 NM_008326
Irgm1
immunity-related GTPase family M member 1
chr9_-_37062963 26.297 Slc37a2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr2_+_129442079 26.223 Sirpa
signal-regulatory protein alpha
chrX_+_104344792 26.072 NM_001122595
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr5_+_115373246 25.829 NM_145209
Oasl1
2'-5' oligoadenylate synthetase-like 1
chr19_+_10917005 25.798 NM_023044
Slc15a3
solute carrier family 15, member 3
chr6_+_57531124 25.151 Herc6
hect domain and RLD 6
chrX_+_104344953 24.887 NM_175442
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr9_-_37063214 24.756 NM_001145960
NM_020258
Slc37a2

solute carrier family 37 (glycerol-3-phosphate transporter), member 2

chr1_-_140071818 24.697 NM_001111316
NM_011210
Ptprc

protein tyrosine phosphatase, receptor type, C

chr5_+_115373333 23.792 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr13_+_24895094 23.328 BC005537
cDNA sequence BC005537
chr19_+_34715368 23.235 NM_008331
Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr11_-_70273251 23.218 Cxcl16
chemokine (C-X-C motif) ligand 16
chr7_-_87532756 23.171 NM_010194
Fes
feline sarcoma oncogene
chr2_+_13504271 22.783


chr2_+_127951773 22.121 NM_009754
NM_207680
NM_207681
Bcl2l11


BCL2-like 11 (apoptosis facilitator)


chr16_-_35939001 21.924 Dtx3l
deltex 3-like (Drosophila)
chr5_+_115373272 21.882 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr18_-_35808986 21.224 NM_027222
2010001M09Rik
RIKEN cDNA 2010001M09 gene
chr18_+_60963495 21.030 NM_001042605
NM_010545
Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

chr4_+_144482979 20.954 NM_011303
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_58494637 20.562 Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chrX_-_9014351 20.393 Cybb
cytochrome b-245, beta polypeptide
chr17_-_71199129 20.209 NM_001164076
Tgif1
TGFB-induced factor homeobox 1
chr10_-_117252126 19.882


chr10_-_61960613 19.529 Srgn
serglycin
chr5_+_115373398 19.261 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr17_+_45704145 18.933 Slc35b2
solute carrier family 35, member B2
chr5_+_20692068 18.815 NM_175437
Pion
pigeon homolog (Drosophila)
chr19_+_9092973 18.514 Ahnak
AHNAK nucleoprotein (desmoyokin)
chr6_+_57530968 18.323 NM_025992
Herc6
hect domain and RLD 6
chr16_-_35939034 17.674 NM_001013371
Dtx3l
deltex 3-like (Drosophila)
chr11_+_59355080 17.562 Nlrp3
NLR family, pyrin domain containing 3
chr7_+_86059105 17.493 NM_001113527
Isg20
interferon-stimulated protein
chr3_+_84470113 17.457 NM_177260
Tmem154
transmembrane protein 154
chr5_+_116081897 17.123 NM_198163
Rab35
RAB35, member RAS oncogene family
chr10_+_42580317 17.110 NM_172938
Scml4
sex comb on midleg-like 4 (Drosophila)
chrX_+_12870471 16.834 Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr7_-_91827857 16.643 NM_022985
Zfand6
zinc finger, AN1-type domain 6
chr11_-_70273190 16.247 Cxcl16
chemokine (C-X-C motif) ligand 16
chr11_-_70273434 16.120 Cxcl16
chemokine (C-X-C motif) ligand 16
chr10_-_18735154 16.116 NM_009397
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr7_+_86058650 16.081 NM_020583
Isg20
interferon-stimulated protein
chr4_-_129235583 16.040 NM_001162432
NM_010693
Lck

lymphocyte protein tyrosine kinase

chr5_-_121227617 15.993 NM_145226
Oas3
2'-5' oligoadenylate synthetase 3
chr1_-_186556046 15.916 Hlx
H2.0-like homeobox
chrX_+_103320051 15.782 Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_164881126 15.630 NM_011611
NM_170702
NM_170703
NM_170704
Cd40



CD40 antigen



chr15_-_76073789 15.422 Parp10
poly (ADP-ribose) polymerase family, member 10
chr3_+_84470230 15.412 Tmem154
transmembrane protein 154
chr1_-_182175890 15.362 NM_011183
Psen2
presenilin 2
chr2_+_121973414 15.155 NM_009735
B2m
beta-2 microglobulin
chr19_-_10813341 15.082 NM_007650
Cd5
CD5 antigen
chr4_-_141430740 14.827 NM_025994
Efhd2
EF hand domain containing 2
chr8_-_74061134 14.813 NM_198095
Bst2
bone marrow stromal cell antigen 2
chr2_+_153171730 14.781 NM_001039939
Asxl1
additional sex combs like 1 (Drosophila)
chr13_-_74908036 14.774 Cast
calpastatin
chr1_+_90003410 14.556 Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr7_+_111392968 14.304 NM_030684
Trim34a
tripartite motif-containing 34A
chr19_+_34644768 14.179 Ifit2
interferon-induced protein with tetratricopeptide repeats 2
chr11_-_69499014 13.704 NM_001159505
NM_023517
Tnfsf13

tumor necrosis factor (ligand) superfamily, member 13

chr9_+_107877887 13.488 NM_023738
Uba7
ubiquitin-like modifier activating enzyme 7
chr7_+_51827801 13.251 NM_008437
Napsa
napsin A aspartic peptidase
chr15_-_9459612 13.088 NM_008372
Il7r
interleukin 7 receptor
chr11_+_101443690 13.073 Tmem106a
transmembrane protein 106A
chr8_+_64406883 13.058 NM_001081215
Ddx60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr9_-_113563906 13.052 Pdcd6ip
programmed cell death 6 interacting protein
chr5_+_104864136 12.909 NM_009263
Spp1
secreted phosphoprotein 1
chr4_+_144483110 12.829 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_-_70273453 12.765 NM_023158
Cxcl16
chemokine (C-X-C motif) ligand 16
chr5_+_104864146 12.508 Spp1
secreted phosphoprotein 1
chr15_-_76073869 12.482 NM_001163575
NM_001163576
Parp10

poly (ADP-ribose) polymerase family, member 10

chr2_-_60589953 12.481 Rbms1
RNA binding motif, single stranded interacting protein 1
chr12_-_56087322 12.434 NM_013815
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr15_-_76073854 12.424 Parp10
poly (ADP-ribose) polymerase family, member 10
chr12_+_109873955 12.243 NM_001163396
Evl
Ena-vasodilator stimulated phosphoprotein
chr15_-_76073582 12.150 Parp10
poly (ADP-ribose) polymerase family, member 10
chr4_-_40186722 12.099 NM_172689
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr5_+_104864168 12.078 Spp1
secreted phosphoprotein 1
chr7_+_86059126 11.990 Isg20
interferon-stimulated protein
chr3_-_104667319 11.942 NM_009797
Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr11_+_95703598 11.942 NM_023121
Gngt2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_+_65221116 11.886 Klf3
Kruppel-like factor 3 (basic)
chrX_+_12869324 11.764 Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr13_+_3553690 11.644 Gdi2
guanosine diphosphate (GDP) dissociation inhibitor 2
chr1_-_157820302 11.642 Cep350
centrosomal protein 350
chr2_+_145647868 11.491 Rin2
Ras and Rab interactor 2
chr3_+_125106995 11.414 NM_022565
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_-_172857670 11.392 NM_001160215
NM_145141
Fcrla

Fc receptor-like A

chr4_+_128670474 11.337 NM_001033966
NM_016895
Ak2

adenylate kinase 2

chr9_-_56265833 10.917 NM_172924
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr8_-_125075222 10.843 NM_001037298
Fam38a
family with sequence similarity 38, member A
chr5_-_66472208 10.782 Rbm47
RNA binding motif protein 47
chr2_+_145648290 10.530 Rin2
Ras and Rab interactor 2
chr7_-_29965500 10.511 Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr12_-_114665550 10.511 Ighg
Immunoglobulin heavy chain (gamma polypeptide)
chr9_-_108961721 10.488 NM_001012236
Trex1
three prime repair exonuclease 1
chr11_-_46202942 10.468 NM_010583
Itk
IL2-inducible T-cell kinase
chr2_-_60589059 10.437 Rbms1
RNA binding motif, single stranded interacting protein 1
chr11_+_101443529 10.392 NM_144830
Tmem106a
transmembrane protein 106A
chr16_+_94906703 10.273 Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr7_-_29965655 10.183 NM_026545
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr16_+_10488270 10.174 NM_007575
Ciita
class II transactivator
chr11_-_70272909 10.141 Cxcl16
chemokine (C-X-C motif) ligand 16
chr10_+_7552260 9.928 NM_172785
Zc3h12d
zinc finger CCCH type containing 12D
chr3_-_104667291 9.888 Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr6_+_121195885 9.854 NM_011909
Usp18
ubiquitin specific peptidase 18
chr4_+_147320793 9.848 2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr19_-_20465115 9.589 Anxa1
annexin A1
chr11_-_115884712 9.446 H3f3b
H3 histone, family 3B
chr16_+_23609986 9.391 NM_023386
Rtp4
receptor transporter protein 4
chr7_-_29965419 9.306 Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr9_-_78327792 9.259 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr2_-_13466273 9.211 NM_010067
Trdmt1
tRNA aspartic acid methyltransferase 1
chr5_-_73143979 9.173 NM_001122754
Txk
TXK tyrosine kinase
chr9_+_108241599 9.169 NM_008160
Gpx1
glutathione peroxidase 1
chr2_-_72817311 9.057 NM_001098425
Sp3
trans-acting transcription factor 3
chr15_-_57702643 8.996 Derl1
Der1-like domain family, member 1
chr10_+_19928244 8.985 NM_001101561
Gm6251
predicted gene 6251
chr9_-_110959315 8.951 Ccrl2
chemokine (C-C motif) receptor-like 2
chr2_+_40412520 8.949 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_34999458 8.936 NM_001142706
NM_008198
Cfb

complement factor B

chr16_-_90727466 8.932 NM_025642
2610039C10Rik
RIKEN cDNA 2610039C10 gene
chr14_+_56223001 8.890 Irf9
interferon regulatory factor 9
chr2_-_34678700 8.855 NM_001164768
Fbxw2
F-box and WD-40 domain protein 2
chr11_-_70273333 8.845 Cxcl16
chemokine (C-X-C motif) ligand 16
chr5_-_138613028 8.819 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_78403110 8.799 NM_009008
Rac2
RAS-related C3 botulinum substrate 2
chr1_+_132762248 8.795 Faim3
Fas apoptotic inhibitory molecule 3
chr3_-_20022409 8.785 Gyg
glycogenin
chr1_-_167865030 8.773 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chr9_+_61220162 8.738 NM_001083927
NM_001083928
NM_009389
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr10_-_87819765 8.709 NM_027878
Dram1
DNA-damage regulated autophagy modulator 1
chr3_+_135128934 8.550 Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr18_-_75120759 8.482 NM_010720
Lipg
lipase, endothelial
chr2_+_17986187 8.442 Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chrX_+_104451216 8.321 NM_001177781
NM_001033251
Gpr174

G protein-coupled receptor 174

chr5_+_65522325 8.294 NM_175174
Klhl5
kelch-like 5 (Drosophila)
chr16_-_3718084 8.258 NM_001161790
NM_001161791
NM_019453
Mefv


Mediterranean fever


chr2_-_59963796 8.256 NM_001001182
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_+_164595389 8.180 Ube2c
ubiquitin-conjugating enzyme E2C
chr5_-_100407613 8.122 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr14_-_56209708 8.060 NM_011190
Psme2
Psme2b-ps
proteasome (prosome, macropain) 28 subunit, beta
protease (prosome, macropain) 28 subunit beta B, pseudogene
chr11_-_103265172 7.931 Plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr11_+_69805051 7.899 Gabarap
gamma-aminobutyric acid receptor associated protein
chr10_+_98486068 7.891 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr13_+_20564928 7.879 NM_198093
Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr3_-_151412812 7.855 NM_133871
Ifi44
interferon-induced protein 44
chr5_-_38893331 7.823 NM_145559
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_82836029 7.771 NM_010472
Agfg1
ArfGAP with FG repeats 1
chr17_+_29629987 7.752 Pim1
proviral integration site 1
chr3_-_58934492 7.742 NM_001008497
NM_133200
P2ry14

purinergic receptor P2Y, G-protein coupled, 14

chr11_-_75114563 7.711 Rpa1
replication protein A1
chr1_+_52176281 7.693 NM_009283
Stat1
signal transducer and activator of transcription 1
chr11_+_75578548 7.628 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr9_-_56265864 7.537 C230081A13Rik
RIKEN cDNA C230081A13 gene
chr9_+_123836859 7.520 NM_009878
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_-_174520562 7.480 NM_029084
Slamf8
SLAM family member 8
chr6_+_83290548 7.388 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr5_-_17341512 7.361 Cd36
CD36 antigen
chr17_-_34999068 7.353 Cfb
complement factor B
chr3_+_123008796 7.309 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr4_-_106812064 7.288 2210012G02Rik
RIKEN cDNA 2210012G02 gene
chr1_-_175810248 7.287 NM_001170853
Mndal
myeloid nuclear differentiation antigen like
chr16_-_98183757 7.285 NM_001081684
NM_001081685
NM_175428
Zfp295


zinc finger protein 295


chr17_+_25270317 7.256 NM_011930
Clcn7
chloride channel 7
chr13_+_63402580 7.097 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr8_-_108461909 6.973 Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr2_+_34631124 6.940 Hspa5
heat shock protein 5
chr1_-_175805812 6.918 Mndal
myeloid nuclear differentiation antigen like
chr9_-_70351520 6.907 NM_033604
Rnf111
ring finger 111
chr10_-_33847745 6.864 NM_175449
Fam26f
family with sequence similarity 26, member F

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.67 1.61e-13 GO:0060255 regulation of macromolecule metabolic process
1.79 1.72e-13 GO:0010468 regulation of gene expression
1.78 2.23e-11 GO:0051252 regulation of RNA metabolic process
1.73 1.31e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.77 1.36e-10 GO:0006355 regulation of transcription, DNA-dependent
1.53 2.64e-10 GO:0019222 regulation of metabolic process
1.70 3.28e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.57 4.09e-10 GO:0080090 regulation of primary metabolic process
1.57 4.79e-10 GO:0031323 regulation of cellular metabolic process
2.29 5.47e-10 GO:0002376 immune system process
1.67 1.11e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 1.70e-09 GO:0044260 cellular macromolecule metabolic process
1.43 1.76e-09 GO:0043170 macromolecule metabolic process
1.65 2.87e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.65 3.85e-09 GO:0031326 regulation of cellular biosynthetic process
1.71 4.77e-09 GO:0048519 negative regulation of biological process
1.63 6.37e-09 GO:0009889 regulation of biosynthetic process
1.61 4.69e-08 GO:0048518 positive regulation of biological process
2.15 1.54e-07 GO:0042127 regulation of cell proliferation
2.08 2.19e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.62 2.60e-07 GO:0048522 positive regulation of cellular process
1.68 2.66e-07 GO:0048523 negative regulation of cellular process
2.02 4.36e-07 GO:0009892 negative regulation of metabolic process
2.06 6.29e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.29 8.70e-07 GO:0010629 negative regulation of gene expression
2.04 9.58e-07 GO:0031324 negative regulation of cellular metabolic process
1.73 1.56e-06 GO:0006351 transcription, DNA-dependent
1.61 1.68e-06 GO:0016070 RNA metabolic process
1.73 1.75e-06 GO:0032774 RNA biosynthetic process
2.31 3.01e-06 GO:0051253 negative regulation of RNA metabolic process
2.00 3.62e-06 GO:0043067 regulation of programmed cell death
1.85 3.89e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.57 3.92e-06 GO:0010467 gene expression
2.31 4.39e-06 GO:0045892 negative regulation of transcription, DNA-dependent
2.22 4.67e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.00 4.69e-06 GO:0042981 regulation of apoptosis
1.30 5.76e-06 GO:0044238 primary metabolic process
1.79 8.46e-06 GO:0009893 positive regulation of metabolic process
1.30 8.97e-06 GO:0044237 cellular metabolic process
1.53 9.17e-06 GO:0090304 nucleic acid metabolic process
1.95 1.22e-05 GO:0010941 regulation of cell death
2.13 2.25e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 2.76e-05 GO:0008152 metabolic process
1.55 3.13e-05 GO:0009059 macromolecule biosynthetic process
2.03 3.17e-05 GO:0010628 positive regulation of gene expression
1.78 4.15e-05 GO:0031325 positive regulation of cellular metabolic process
2.14 4.30e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.90 4.57e-05 GO:0050793 regulation of developmental process
1.54 5.39e-05 GO:0034645 cellular macromolecule biosynthetic process
2.06 6.75e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 6.88e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.11 7.50e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.50 7.80e-05 GO:0009607 response to biotic stimulus
2.06 7.84e-05 GO:0031327 negative regulation of cellular biosynthetic process
4.47 7.96e-05 GO:0050870 positive regulation of T cell activation
1.96 1.09e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02 1.19e-04 GO:0051254 positive regulation of RNA metabolic process
2.63 1.87e-04 GO:0051707 response to other organism
2.01 1.88e-04 GO:0009890 negative regulation of biosynthetic process
1.91 2.89e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.90 4.07e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
3.59 4.28e-04 GO:0051251 positive regulation of lymphocyte activation
1.90 5.00e-04 GO:2000026 regulation of multicellular organismal development
1.64 5.07e-04 GO:0048583 regulation of response to stimulus
2.10 6.66e-04 GO:0002682 regulation of immune system process
2.34 6.99e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.20 7.34e-04 GO:0065007 biological regulation
1.95 7.45e-04 GO:0045595 regulation of cell differentiation
2.13 7.49e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.38 8.51e-04 GO:0006807 nitrogen compound metabolic process
2.98 9.22e-04 GO:0051249 regulation of lymphocyte activation
2.39 1.02e-03 GO:0006955 immune response
3.39 1.15e-03 GO:0050863 regulation of T cell activation
2.24 1.19e-03 GO:0043069 negative regulation of programmed cell death
1.64 1.38e-03 GO:0051239 regulation of multicellular organismal process
1.82 1.45e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.81 1.51e-03 GO:0009891 positive regulation of biosynthetic process
1.37 1.68e-03 GO:0034641 cellular nitrogen compound metabolic process
1.98 1.72e-03 GO:0008219 cell death
3.30 1.84e-03 GO:0002696 positive regulation of leukocyte activation
1.20 1.86e-03 GO:0050789 regulation of biological process
4.51 1.97e-03 GO:0048660 regulation of smooth muscle cell proliferation
2.22 2.06e-03 GO:0043066 negative regulation of apoptosis
1.57 2.12e-03 GO:0048513 organ development
1.96 2.41e-03 GO:0016265 death
1.42 2.46e-03 GO:0016043 cellular component organization
2.40 2.56e-03 GO:0002520 immune system development
2.31 2.60e-03 GO:0045597 positive regulation of cell differentiation
2.33 2.73e-03 GO:0010627 regulation of intracellular protein kinase cascade
2.76 2.79e-03 GO:0002694 regulation of leukocyte activation
1.75 2.96e-03 GO:0010033 response to organic substance
2.14 3.18e-03 GO:0051704 multi-organism process
2.44 3.56e-03 GO:0008283 cell proliferation
3.18 3.58e-03 GO:0050867 positive regulation of cell activation
2.15 3.65e-03 GO:0060548 negative regulation of cell death
1.13 3.77e-03 GO:0009987 cellular process
2.30 4.02e-03 GO:0051240 positive regulation of multicellular organismal process
2.08 5.07e-03 GO:0008284 positive regulation of cell proliferation
2.39 5.81e-03 GO:0048534 hemopoietic or lymphoid organ development
1.39 6.31e-03 GO:0071840 cellular component organization or biogenesis
2.76 6.39e-03 GO:0046649 lymphocyte activation
2.64 6.44e-03 GO:0050865 regulation of cell activation
2.08 7.25e-03 GO:0006952 defense response
1.38 9.54e-03 GO:0044249 cellular biosynthetic process
2.53 1.04e-02 GO:0045321 leukocyte activation
2.08 1.13e-02 GO:0043065 positive regulation of apoptosis
3.94 1.16e-02 GO:0002819 regulation of adaptive immune response
2.03 1.35e-02 GO:0051094 positive regulation of developmental process
1.93 1.36e-02 GO:0012501 programmed cell death
2.06 1.40e-02 GO:0043068 positive regulation of programmed cell death
1.36 1.66e-02 GO:0009058 biosynthetic process
1.58 1.72e-02 GO:0006996 organelle organization
1.93 1.75e-02 GO:0006915 apoptosis
1.51 1.92e-02 GO:0042221 response to chemical stimulus
3.29 1.94e-02 GO:0030098 lymphocyte differentiation
3.14 2.14e-02 GO:0001819 positive regulation of cytokine production
2.01 2.24e-02 GO:0048646 anatomical structure formation involved in morphogenesis
4.92 2.32e-02 GO:0045621 positive regulation of lymphocyte differentiation
2.38 2.43e-02 GO:0030097 hemopoiesis
2.02 2.47e-02 GO:0010942 positive regulation of cell death
2.62 2.53e-02 GO:0030036 actin cytoskeleton organization
2.56 2.57e-02 GO:0030029 actin filament-based process
1.62 2.81e-02 GO:0033036 macromolecule localization
1.79 2.93e-02 GO:0015031 protein transport
2.97 3.06e-02 GO:0002252 immune effector process
3.80 3.57e-02 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
5.19 3.58e-02 GO:0045582 positive regulation of T cell differentiation
2.13 3.98e-02 GO:0002684 positive regulation of immune system process
2.72 4.76e-02 GO:0051223 regulation of protein transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.27 6.68e-15 GO:0005622 intracellular
1.27 1.17e-14 GO:0044424 intracellular part
1.50 3.51e-13 GO:0005634 nucleus
1.30 4.11e-13 GO:0043226 organelle
1.30 6.70e-13 GO:0043229 intracellular organelle
1.32 9.00e-12 GO:0043227 membrane-bounded organelle
1.31 1.75e-11 GO:0043231 intracellular membrane-bounded organelle
1.27 5.01e-08 GO:0005737 cytoplasm
1.11 1.24e-05 GO:0005623 cell
1.11 1.24e-05 GO:0044464 cell part
1.37 2.19e-05 GO:0044422 organelle part
1.37 2.45e-05 GO:0044446 intracellular organelle part
1.62 2.54e-05 GO:0044428 nuclear part
1.47 2.93e-05 GO:0043234 protein complex
1.41 6.15e-05 GO:0032991 macromolecular complex
1.77 3.30e-04 GO:0005654 nucleoplasm
1.62 3.41e-04 GO:0005829 cytosol
1.96 3.81e-04 GO:0044451 nucleoplasm part
1.60 8.12e-04 GO:0031981 nuclear lumen
1.47 1.24e-02 GO:0031974 membrane-enclosed lumen
1.47 1.31e-02 GO:0070013 intracellular organelle lumen
1.47 1.41e-02 GO:0043233 organelle lumen
1.37 2.17e-02 GO:0043228 non-membrane-bounded organelle
1.37 2.17e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.22 2.72e-02 GO:0044444 cytoplasmic part
2.79 4.03e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.27 3.27e-14 GO:0005488 binding
1.47 4.29e-14 GO:0005515 protein binding
1.69 1.06e-10 GO:0003676 nucleic acid binding
1.86 2.30e-10 GO:0003677 DNA binding
2.11 8.11e-08 GO:0030528 transcription regulator activity
2.27 5.12e-07 GO:0043565 sequence-specific DNA binding
2.06 1.07e-05 GO:0001071 nucleic acid binding transcription factor activity
2.06 1.07e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
3.21 2.40e-05 GO:0043566 structure-specific DNA binding
2.49 2.34e-04 GO:0016563 transcription activator activity
1.63 1.00e-03 GO:0008270 zinc ion binding
1.56 1.09e-03 GO:0046914 transition metal ion binding
2.29 7.92e-03 GO:0008134 transcription factor binding
2.26 1.02e-02 GO:0016564 transcription repressor activity
2.91 2.20e-02 GO:0003690 double-stranded DNA binding
1.73 4.48e-02 GO:0003723 RNA binding